5 edition of Molecular motors and the cytoskeleton found in the catalog.
Molecular motors and the cytoskeleton
Includes bibliographical references and indexes.
|Statement||edited by Richard B. Vallee.|
|Series||Methods in enzymology -- v. 298.|
|Contributions||Vallee, Richard B.|
|The Physical Object|
|Pagination||xxx, 559 p. :|
|Number of Pages||559|
Motor proteins are molecular machines that convert chemical energy from ATP hydrolysis into mechanical work, which powers cell motility. Over the last ten years, single-molecule techniques and structural studies have led to rapid progess in understanding how these biological motors operate. Most cell and molecular biology textbooks are content to discuss the cytoskeleton, and the ‘‘motor proteins’’ that move and contract it, purely in terms of phylogeny, regulation, basic.
The movements of single motor-protein molecules can be analyzed directly. Using polarized laser light, it is possible to create interference patterns that exert a centrally directed force, ranging from zero at the center to a few piconewtons at the periphery (about nm from the center). Molecular motors walking on the cytoskeleton facilitate active intracellular transport, which is more efficient than diffusion‐based passive transport. Active transport driven by kinesin and dynein walking on microtubules has been studied well during recent decades. However, mechanisms of active transport occurring in disorganized actin.
Molecular motors are enzymes that transform chemical energy into mechanical work. In the cytoplasm of eukaryotic cells, three different classes of motors that generate linear movement are known to exist – myosin, kinesin and dynein. Figure 1 shows prototypical representatives of these motor classes. Abstract: The mechanics of cells is strongly affected by molecular motors that generate forces in the cellular cytoskeleton. We develop a model for cytoskeletal networks driven out of equilibrium by molecular motors exerting transient contractile stresses.
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Purchase Molecular Motors and the Cytoskeleton, Part B, Volume - 1st Edition. Print Book & E-Book. ISBNBook Edition: 1.
Purchase Molecular Motors and the Cytoskeleton, Volume - 1st Edition. Print Book & E-Book. ISBNSearch in this book series. Molecular Motors and the Cytoskeleton. Richard B. Vallee. VolumePages () Download full volume.
Previous volume. Next volume. Actions for selected chapters. Select all / Deselect all. Download PDFs Export citations. Show all. On actin microfilaments, the molecular motors are proteins of the myosin family. At this point, the analogies end, as the functioning of these molecular motors is very different from locomotion by train or truck.
Finally, one might question the biological need for such a transport system. Search in this book series. Molecular Motors and the Cytoskeleton Part B. Richard B. Valee.
VolumePages () Download full volume. Previous volume. Next volume. Actions for selected chapters. Select all / Deselect all. Download PDFs Export citations. Books Molecular Motors and the Cytoskeleton, Part B, Volume (Methods in Enzymology) Full Online. RobbynSandavol.
Audiobook Molecular Motors: Methods and Protocols (Methods in Molecular Biology) For Kindle. vigos. Definition and Brief explanation [ edit | edit source]. Molecular motors are enzyme protein devices that move along cytoskeletal filaments and the proteins are run by ATP hydrolysis.
The main system of Biological motility is driven by the factor of intracellular motility. For example, the microtubules and the actin filaments in cells are tracks, and the molecular motors have two parts the. The book is well organized into three primary parts: Physical Principles, Cytoskeleton, and Motor Proteins.
If an engineer is interested in nothing more than gaining insight into the relevant physics at the molecular level, then the book is worth purchasing simply for the well-written section devoted to Part I: Physical Principles.
Molecular motors are natural (biological) or artificial molecular machines that are the essential agents of movement in living organisms. In general terms, a motor is a device that consumes energy in one form and converts it into motion or mechanical work; for example, many protein-based molecular motors harness the chemical free energy released by the hydrolysis of ATP in order to perform.
Eukaryotic cells depend on cytoskeletal polymers and molecular motors to establish their asymmetrical shapes, to transport intracellular constituents and to drive their motility. Cell biologists. It comprises three major filament systems-actin, microtubules, and intermediate filaments-along with a host of adaptors, regulators, molecular motors, and additional structural proteins.
This textbook presents a comprehensive and up-to-date view of the cytoskeleton, cataloguing its many different components and explaining how they are. Molecular Motors and the Cytoskeleton, Part B: Volume by John N.
Abelson (Editor), Melvin I. Simon (Editor), Richard B. Vallee (Editor) & ISBN ISBN Why is ISBN important. ISBN. This bar-code number lets you verify that you're getting exactly the right version or edition of a book. Format: Paperback. ISBN: OCLC Number: Notes: Fait suite aux 2 vol. parus sous le titre: Structural and contractile proteins: the contractile apparatus and the cytoskeleton (Methods in enzymology ; vol.
85 ; vol. The cytoskeleton pulls the chromosomes apart at mitosis and then splits the dividing cell into two. It drives and guides the intracellular traffic of organelles, ferrying materials from one part of the cell to another. It supports the fragile plasma membrane and provides the mechanical linkages that let the cell bear stresses and strains without being ripped apart as the environment shifts and.
Molecular motors and the cytoskeleton. [Richard B Vallee;] Home. WorldCat Home About WorldCat Help. Search. Search for Library Items Search for Lists Search for Book: All Authors / Contributors: Richard B Vallee.
Find more information about: ISBN: OCLC. Structural biology and cytoskeleton motors in neuron. A large number of structural studies have greatly enhanced our understanding of neurological functions of many cytoskeleton motors.
We summarize a few recent cases as examples to highlight the power and uniqueness of structural biology in uncovering the molecular mechanisms of cytoskeleton.
Motors moving on cytoskeletal filaments can be classified into three types: myosins, kinesins and dyneins as shown in Figure 1. Though the diversity of these motors mirrors that of life more generally, we can attempt to classify them broadly into those that move on actin filaments and those that move on microtubules and according to the directionality of their motion.
Vallee, Richard B.Molecular motors and the cytoskeleton / edited by Richard B. Vallee Academic Press Inc New York [etc.] Wikipedia Citation Please see Wikipedia's template documentation for further citation fields that may be required.
This book is for biology, physics, and engineering students who want to learn about the principles of protein mechanics and how it applies to the morphology and motility of cells.
Understanding how motors and the cytoskeleton operate requires mechanical concepts such. Vermont Molecular Motors; Virtual Library of Biochemistry & Cell Biology: Cytoskeleton, Cell Motility, & Motors; Virtual Tour of the African Trypanosome Cytoskeleton; W.M. Keck Dynamic Image Analysis Facility (Cell Motility Center) at the University of Iowa; Cytoskeleton Books.
Cell Migration in Development and Disease (Editor: Doris Wedlich. Cytoskeleton motors comprise of myosin, kinesin and cytoplasmic dynein.
F-actin filaments act as myosin track, while kinesin and cytoplasmic dynein move on microtubules. Cytoskeleton motors work together to build a highly polarized and regulated system in neuronal cells via different molecular mechanisms and functional regulations.The Cytoskeleton Motor Werks™ (CMW) product line is exclusively manufactured and sold by Cytoskeleton.
These products facilitate the progress of research and drug discovery in the motor protein area (Funk et al. ). We focus on producing highly pure and biologically active kinesin and myosin family proteins of eukaryotic and fungal origin. Motor proteins are molecular machines that convert chemical energy from ATP hydrolysis into mechanical work, which powers cell motility.
Over the last ten years, single-molecule techniques and structural studies have led to rapid progess in understanding how these biological motors /5(1).